| Ecosystem | Type | Status | Ref. |
|---|---|---|---|
| Atlantic Ocean | Sea/Bay/Gulf | native | 5723 |
| Chesapeake Bay | Sea/Bay/Gulf | Native | 93252 |
| Colorado River | River (basin) | introduced | 86798 |
| Great Lakes | Lake | introduced | 86798 |
| Gulf of Maine | Sea/Bay/Gulf | native | 86779 |
| Lake Erie | Lake | introduced | 53249 |
| Lake Huron | Lake | introduced | 120881 |
| Lake Michigan | Lake | introduced | 86798 |
| Lake Ontario | Lake | introduced | 120883 |
| Lake Superior | Lake | introduced | 120875 |
| Mississippi River | River (basin) | native | 78789 |
| Missouri River | River (basin) | native | 78789 |
| Nearctic | Zoogeographic realm | endemic | 6399 |
| Northeast U.S. Continental Shelf | Sea/Bay/Gulf | native | 5723 |
| Ohio River | River (basin) | native | 86798 |
| Savannah River | River (basin) | native | 86798 |
| Scotian Shelf | Sea/Bay/Gulf | native | 7251 |
| Southeast U.S. Continental Shelf | Sea/Bay/Gulf | native | 7251 |
| St. Lawrence | River (basin) | native | 5723 |
| Waccamaw | Lake | native | 35360 |